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Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure that is widely used to sample mediastinal lesions, hilar lesions, and lesions adjacent to the central airway.(1,2) EBUS-TBNA was originally performed using dedicated 22-gauge needles. Recently, 21-gauge needles have been employed to improve the quality of biopsy specimens. The relative sampling utility of 21-gauge needles, in comparison with that of 22-gauge needles, remains controversial.

Evaluation of the gauge of needles used in the collection of specimens during endobronchial ultrasound-guided transbronchial needle aspiration