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Purpose: To analyze how small and medium enterprises (SMEs) coordinate collaborative research and development (R&amp;D) projects through an open innovation strategy. Originality/value: This research was motivated by a theoretical gap in the management of collaborative R&amp;D projects in open innovation strategies. The originality of the paper is to advance the understanding of coordination mechanisms that SMEs can use to manage open innovation and obtain more effective results. Design/methodology/approach: The research followed a qualitative approach, through three case studies of collaborative projects. Data were collected by means of in-depth interviews with eleven managers directly involved in collaborative R&amp;D projects. Findings: Results demonstrate that the use of coordination mechanisms depends on the applicability of each project’s results, i.e., the higher the chances of a certain R&amp;D project becoming a real product, the higher the importance given to the coordination mechanisms. On the cases observed, the coordination mechanisms were defined by the enterprise, not by external partners. In addition, it was observed that open innovation projects that the enterprise seeks for external knowledge to complement internal resources (outside-in) were considered more important than transferring internal knowledge to external partners (inside-out). The paper contributes to organizational theory by highlighting the relation between the characteristics of collaborative R&amp;D projects and the coordination mechanisms used. Regarding the managerial contribution, results serve as a guide for entrepreneurs and managers of SMEs interested in coordinating collaborative projects based on open innovation processes.

COORDINATION MECHANISMS OF COLLABORATIVE R&D PROJECTS IN SMALL AND MEDIUM ENTERPRISES