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EnglishThe aqueous extract of Aristolochia triangularis leaves showed activity against Artemia salina larvae, with an LD50 of 370.6 µg/ mL. In experiments with Allium cepa seeds, the extract caused a 51.26% reduction in the germination index, inhibited mean root growth, and was cytotoxic at concentrations of 668 and 2,000 µg/mL. Its antioxidant activity was additionally assessed in this research and the ferric reducing antioxidant power value was found to be 391.2 µM/g. Such health-beneficial property can be attributed partly to the total phenolic content, spectrophotometrically determined as 52.67 mg/g. The occurrence of cytotoxicity suggested caution when consuming teas from A. triangularis leaves for medicinal purposes, and equally reveals the need for further studies to investigate their adverse effects. portuguesO extrato aquoso de folhas de Aristolochia triangularis mostrou atividade sobre larvas de Artemia salina, com um DL50 de 370,6 µg/mL. Em experimentos com sementes de Allium cepa, o extrato provocou uma reducao de 51,26% no indice de germinacao, inibiu o crescimento radicular medio e foi citotoxico nas concentracoes de 668 e 2.000 µg/mL. Sua atividade antioxidante foi adicionalmente avaliada nesta pesquisa e o valor de poder redutor de ions ferrico foi de 391,2 µM/g. Tal propriedade benefica para a saude pode ser parcialmente atribuida ao conteudo de compostos fenolicos totais, espectrofotometricamente determinada como 52,67 mg/g. A ocorrencia de citotoxicidade sugeriu cautela ao consumir chas de folhas de A. triangularis para propositos medicinais, e igualmente revela a necessidade por estudos adicionais para investigar os efeitos adversos deles.

Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays