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Changes to architectural projects can be seen as an ongoing process from design concept to use. This paper analyses a particular phase of an architectural project, the start-up, which is characterized by the initial occupation of a workplace by users and the start-up of services. This paper aims to show that the experiences in this phase are unique and may make specific contributions to the design process. Analysis during the start-up phase may reveal experiences and users'needs that have not been met by designers, as well as inadequacies in the newly built space. This paper presents the results of a case study carried out in a sector of a hospital dedicated to patients with HIV. The analysis of the start-up of this newly constructed centre was performed using two methodologies: Post-Occupancy Evaluation and Ergonomic Work Analysis. The results suggest that ergonomic interventions in projects should encompass the start-up phase

Users contributions to an architectural project at the start up