English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

BACKGROUND   Opportunistic pathogenic yeast species are frequently associated with water habitats that have pollution sources of human or animal origin.  Candida albicans  has already been suggested as a faecal indicator microorganism for aquatic environments.    OBJECTIVES   The goal of this study was to investigate the occurrence of  C. albicans  and other opportunistic yeasts in sand and seawater samples from beaches in Brazil to assess their correlation with  Escherichia coli , and to characterise the pathogenic potential of the yeast isolates.    METHODS   Opportunistic species (yeasts that grow at 37ºC) were isolated from sand and seawater samples from eight beaches in Brazil during the summer and the winter. Opportunistic yeast species were evaluated for their susceptibility to antifungal drugs, virulence factors, and the  in vitro  and  in vivo  biofilm formation. Strains were selected to carry out virulence tests using BALB/c mice.    FINDINGS   Several water samples could be classified as inappropriate for primary contact recreation in relation to  E. coli  densities.  C. albicans  was isolated in low densities. Of the 144 opportunistic yeasts evaluated, 61% displayed resistance or dose-dependent sensitivity to at least one tested drug, and 40% produced proteinase. Strains of  C. albicans  and  Kodamaea ohmeri  exhibited the highest rates of adhesion to buccal epithelial cells. All the  C. albicans  strains that were tested were able to undergo morphogenesis and form a biofilm on catheter fragments in both  in vitro  and  in vivo  experiments. It was possible to confirm the pathogenic potential of three of these strains during the disseminated infection test.    MAIN CONCLUSIONS   The identification of opportunistic yeast species in seawater and sand samples from Brazilian beaches suggest a potential risk to the health of people who use these environments for recreational purposes.

Occurrence, antifungal susceptibility, and virulence factors of opportunistic yeasts isolated from Brazilian beaches