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[1]. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Departamento de Ensino e Pesquisa, Manaus, AM, Brasil. [2]. Universidade do Estado do Amazonas, Programa de Pós-Graduação em Medicina Tropical, Manaus, AM, Brasil. [3]. Instituto Nacional de Infectologia Carlos Chagas, Rio de Janeiro, RJ, Brasil. [4]. Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Rio de Janeiro, RJ. Brasil. [5]. Fundação Oswaldo Cruz, Instituto de Pesquisas Leônidas e Maria Deane, Manaus, AM, Brasil.

Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes