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Objetive: To investigate the association between analgesia during labor and occurrence of neonatal outcomes.  Method: Retrospective cohort study with medical records of 850 parturient. The exposure variable of interest was receiving pharmacological analgesia during labor and neonatal outcomes were: one- and five-minute Apgar, resuscitation maneuvers and referral of the newborn to Neonatal ICU. A logistic regression was carried out to obtain Odds Ratios and 95% confidence interval, with adjustment for confounding factors.  Results: Among the women studied, 35% received analgesia and this use was associated with a greater chance of neonatal outcomes such as one-minute Apgar &lt; 7 (p &lt;0.0001), resuscitation maneuvers (p &lt;0.001) and referral to the Neonatal ICU (p = 0.004), mostly were among low-risk pregnant women, even after adjustments.  Conclusion: The use of pharmacological analgesia during labor is associated with one-minute Apgar &lt; 7, resuscitation maneuvers and referral to the Neonatal ICU.

Obstetric analgesia in labor and its association with neonatal outcomes