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On the basis modified Hans reaction and with the presence of various catalysts has been synthesized optically active methyl 2,7,7-trimethyl-5-oxo-4(4-methoxyphenyl) -1,4,5,6,7,8-hexahydroxinoline-3carboxylate. The degree of optical purity of the synthesized compound was studied by HPLC analysis. Factors influencing to the practical output of the reaction and the degree of optical purity of the synthesized compound were studied in comparative form in twoand three-component reactions.

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THE SYNTHESIS OF OPTICALLY ACTIVE METHYL 2,7,7-TRIMETHYL-5-OXO-4- (4-METHOXYPHENYL) -1,4,5,6,7,8-HEXAHYDROXYNOLIN-3-CARBOXYLATE BASED ON MODIFIED HANS REACTION.