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Twelve multigenerational families with the generalized epilepsy and febrile seizure plus (GEFS+) syndrome and a known clinically relevant epilepsy gene mutation were examined for age of onset of febrile seizures (FS or FS+), in a study at the University of Melbourne, Australia, and centers in the Netherlands and Israel.

Influence of SCN1A Gene Mutation on Age of Onset of Febrile Seizures in GEFS+