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kocytes), as well as elevated levels of NT-proBNP (3784 pg/mL). He was then referred to our center from a local hospital. Initial echocardiographic examination revealed a slightly dilated left ventricle, with signs of a restrictive cardiomyopathy. Apical 4 chamber view revealed that the apex of the left ventricle is obliterated by a substance, suspected a thrombus formation (Figure 1). Magnetic resonance performed with gadolinium contrast revealed diffuse fibrosis of the endocardium and a severely hypokinetic apex of the left ventricle, filled with a thrombus mass (dimensions: 2.7x2.5cm), concluding that the finding is characteristic for endocardial fibroelastosis. In coordination with a hematologist, the patient was started on imatinib, for the eosinophilia, and low molecular weight heparin, as well optimal medical treatment for heart failure. During one of the scheduled checkups, a follow up echocardiographic examination revealed a significant reduction in the overall size of the thrombus mass, but now, with a peduncular formation protruding into the ventricle, moving freely in the blood current (Figure 2). At that time, the patient had exhibited a significant clinical improvement, and was regularly Nina Jakuš*, Ivo Planinc, Hrvoje Jurin, Marijan Pašalić, Dora Fabijanović, Daniel Lovrić, Boško Skorić, Jure Samardžić, Jana Ljubas Maček, Hrvoje Gašparović, Bojan Biočina, Maja Čikeš, Davor Miličić

Therapeutic challenges in treatment of a restrictive cardiomyopathy due to hypereosinophilic syndrome in a young patient: a case report