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pACIJENTI I mETOdE: U ovu presjecnu studiju bili su ukljuceni SSc bolesnici s ocuvanom istisnom frakcijom lijeve klijetke, 13 bolesnika s LVDD te 13 bolesnika bez LVDD podudarnih po dobi, spolu, indeksu tjelesne mase i navici pusenja. Postojanje LVDD je bilo definirano i klasificirano prema smjernicama American Society of Echocardiography. Svi ispitanici su bili podvrgnuti klinickom pregledu, seroloskoj analizi i ehokardiografskoj procijeni srcane funkcije, ukljucujuci metodu pulsnog tkivnog Dopplera te procjeni kardiopulmonalne sposobnosti 6-minutnim testom hodanja (6MWT).

Clinical and laboratory differences between patients diagnosed with systemic sclerosis with and without diastolic dysfunction