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On oncology patients, the risk of developing a second tumor induced by radiation is justified by the treatment benefits. However, in Hodgkin’s lymphoma patients, if any effectively radiation free methods are available, they should be preferred. We correlated WB-MRI/DWI and FDG-PET/CT findings in children, adolescents and young adults with Hodgkin’s lymphoma, and evaluated whether the former can be used in patient’s staging and follow-up protocols as a surrogate of methods that use ionizing radiation. The patients’ age at image acquisition was from 6.6 to 19.8 years (mean of 15.6 ± 3.5 years). 21 studies (63.6%) were from male while 12 (36.4%) were female patients. The WB-MRI/DWI and FDG-PET/CT imaging were performed on a mean of 7.6 ± 4.9 days. We found r = 0.831 (p<0.001) for the number of positive sites and r = 0.863 (p<0.001) for their largest diameters. Kappa concordance correlation coefficient demonstrated a sensitivity of 96% and a specificity of 95%, with 95.2% of concordance to FDG-PET/CT and Kappa index of 0.8004 (p <0.001). WB-MRI/DWI is a safe and valuable method, with very strong Pearson correlation and almost perfect Kappa agreement with the FDG-PET/CT, which can be used as an alternative in the evaluation of children, adolescents and young adults with Hodgkin’s lymphoma. *Correspondence to: José Luiz de Oliveira Schiavon, Department of Diagnostic Imaging, Rua Adalberto Ferraz 361 AP 1301, Centro, Pouso Alegre – MG, 37550-105, Brazil, Tel : +55 35-997572370; E-mail: schiavon00@gmail.com

Whole body MRI with diffusion sequence Versus FDG-PET/CT: Correlation study on children, adolescents and young adults with Hodgkin lymphoma