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Squamous cell carcinoma (SCC) of the tongue typically presents with mucosal lesions. Here, we describe a patient presenting with a tender mass of the tongue and intermittent fevers, though with normal overlying mucosa on exam. Computed tomography (CT) revealed what appeared to be a lingual abscess, and she was brought to the operating room (OR) for incision and drainage (I&D). Given the concerns for an occult cancer, a biopsy was performed and revealed SCC. Here we discuss the implications of this bizarre presentation of a tongue malignancy and review published literature on similar cases. Thus far, this is the first reported case of a primary tongue SCC lacking mucosal involvement. *Correspondence to: Karthik Rajasekaran, Department of OtorhinolaryngologyHead and Neck Surgery, University of Pennsylvania, Philadelphia, USA, Tel: 215-829-5180; E-mail: Karthik.Rajasekaran@pennmedicine.upenn.edu

Submucosal squamous cell carcinoma of the oral tongue presenting as lingual abscess