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Unstable angina may present as transient episodes of myocardial ischemia in different clinical presentations. The use of myocardial perfusion imaging (MPI) in the emergency department (ED) for the accurate diagnosis of unstable angina, in patients with a non-diagnostic ECG seems to be a safe, accurate and potentially costeffective management technique. The use of MPI allows the measurement of myocardial area at risk, infarct size, collateral flow to the infarcted zone and subsequently, myocardial salvage during reperfusion therapy. Therefore, the determination of myocardium at risk for earlier intervention and the reduction in the extent of the affected area following intervention comprises a promising measurement technique for the assessment of  acute  therapy. This technique has provided significant advances in the field of imaging through efficient triaging of patients having chest pain indicative of unstable angina. *Correspondence to: Sudarshana Datta, MD, Baim Institute for Clinical Research 930 Commonwealth Ave Boston, MA 02215, United States, Tel: + (617) 800-6637; E-mail: sdatta2@bidmc.harvard.edu Received: April 25, 2018; Accepted: May 10, 2018; Published: May 18, 2018 Myocardial perfusion imaging MPI is a stress imaging modality used commonly in the treatment of coronary artery disease (CAD). Through detection of flow-limiting disease, assessment and quantification of patient risk, MPI is helpful in the evaluation of the presence and severity of CAD. A large number of MPI studies are done with gated single-photon emission computed tomography (SPECT), and more than 50% are done with vasodilator stress. Gated positron emission tomography (PET), which is nowadays increasingly being used for MPI, provides crucial information such as the severity and the extent of myocardial perfusion abnormalities, mechanical dyssynchrony, myocardial ischemia and left ventricular (LV) function and size. Based on past literature, MPI at rest is a valuable guide to patient management [1].

Review of myocardial perfusion imaging in the state of unstable angina