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Context: Sickle cell disease is an inherited disease of hemoglobin, which is manifested primarily by vaso-occlusive or hemolytic crises and often requires a recurrent therapeutic transfusion. Its prevalence in sub-Saharan Africa is very high. Objective: To establish seroprevalence of HIV in polytransfused adult homozygous sickle cell patients at the Center of Mixed Medicine and Anemia SS (CMMASS) in Kinshasa. Methods: A retrospective study was conducted at the CMMASS between January 2006 and June 2017 to determine the number of confirmed cases of HIV infection in homozygous adult polytransfused patients. Have been included, all patients diagnosed by electrophoresis of hemoglobin and who received a minimum of 2 blood transfusions during the study period. Results: One hundred and eighty (180) patients constituted the study sample. The age was in the range of 18 to 50 years with a median of 29 years. The most represented age group was 18 to 23 years (48.33%). The female gender was the most represented (64.44%) with a sex ratio of 1.77 (women / men). HIV seroprevalence was of 8.33% (N = 15). Conclusion: The seroprevalence of HIV in the population of polytransfused adult sickle cell disease at the Center of Mixed Medicine and Anemia SS of Kinshasa is 8.33% for the interval from 2006 to 2017. *Correspondence to: Erick Kamangu, Research Group "HIV/AIDS Focus", KinshasaDemocratic Republic of the Congo, E-mail: erick.kamangu@unikin.ac.cd

Seroprevalence of HIV in polytransfused adult sickle cell disease: Case of the center of mixed medicine and SS anemia of kinshasa