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Received: May 07, 2018; Accepted: May 18, 2018; Published: May 25, 2018 Obesity is a marker of the clustering of metabolic risk factors for coronary heart disease (CHD) [1,2] and obesity itself is also an independent risk factor of CHD among white populations [3-6]. Obesity is not prevalent in Japan and the prevalence of CHD in Japan has been reported to be the lowest among developed countries [7,8]. The low prevalence of obesity and CHD in Japan may partly result from the low-fat vegetableand fish-rich Japanese diet [9,10]. There have been conflicting data regarding the relationship between obesity and CHD in Japan [11-18]. Some studies have suggested a significant association between obesity and CHD in Japanese [11,13] but others have found opposite results [12,15,17,18]. A case-control study suggested that obesity is independently associated with acute myocardial infarction (AMI) in young and middle-aged men, but not in women and older men [16]. The ageand sex-related differences in the association between risk factors of CHD and abdominal obesity might contribute, at least in part, to these conflicting data in Japan [19]. So, we investigated the ageand sex-related association between obesity and AMI after controlling for diabetes, hypertension, hypercholesterolemia, and smoking in ageand sex-matched case-control samples in Japan [20].

Mini-report on the association between obesity and acute myocardial infarction in Japanese