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To analyze the parameters including data of disease progression, muscles power subsidence, life expectancy, functional independence and rates of cognitive disturbances, which were obtained during observation of the patients with amyotrophic lateral sclerosis (ALS) who were administered a combined therapy by use of fetal stem cells (FSCs) extracted from human fetuses with 5-10 weeks of gestation along with a complex of bodily exercises within the whole period of the follow-up. A comparative study of 56 patients suffering from different forms of ALS was performed. The main group (MG) included 30 patients who were administered a combined treatment comprising the individual program with a complex of kinesiotherapy, respiratory gymnastics and transplantation of suspensions containing fetal stem cells (FSCs) harvested from fetal liver and brain of human fetuses with 5-10 weeks of gestation over the period of observation. The control group (CG) constituted 26 patients who followed their individual programs including a complex of kinesiotherapy and respiratory gymnastics during observation. The patients in both groups were compared according to the sex, age and the forms of ALS disease. Significant slowdown of the course of ALS disease and prolongation of average life expectancy was reported over a period from 6 to 18 months after treatment among the patients of the MG in comparison with the patients of the CG. Suggested method of treatment encourages searching for more effective management of ALS and extension of life expectancy in the patients, even though, it demands maintenance of further clinical studies. Combined treatment of ALS including the individual program with a complex of kinesiotherapy, respiratory gymnastics and administration of FSCs suspensions proved to objectively inhibit a progression of ALS over the period from 6 to 18 months from the beginning of treatment and contributes to longer life expectancy among the patients.

Combined therapy using fetal stem cells and a complex of physical exercises in treatment of patients with amyotrophic lateral sclerosis