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Background: The occurrence of exacerbation in these patients may result in worsening quality of life and a faster decline in lung function. Amongst the Indian population the prevalence of COPD is about 3% to 8% in males and 2.5% to 4.5% in females. Objective: The purpose of this study was to analyze the effectiveness of treatment and the quality of life of those patients who were admitted with a diagnosis of AECOPD to Amrita Institute of Medical Sciences and Research Centre, Kerala between October 2018 and April 2019. The patients selected were those who had received a combination of formoterol with budesonide to the standard treatment of salbutamol with ipratropium bromide nebulization. Methods: A total of 75 patients with diagnosis of acute exacerbation of COPD met the inclusion criteria. Their dyspnea symptoms, Arterial blood gas (ABG) values, PEFR values and their quality of life were compared on day of admission and day of discharge. The ADRs that occurred were also monitored during their stay at the hospital. Result: There was a significant change in the effectiveness parameters and the quality of life of the patients who were taking the treatment together. The ADRs observed were not severe Conclusion: The use of the treatment combination showed a statistical significance in the patient’s condition hence showing that the addition of formoterol and budesonide to the standard therapy may be considered in the treatment of patients suffering from acute exacerbated COPD. *Correspondence to: Jyothisree Vijay, Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, Kerala, India, E-mail: jo21vijay@gmail.com

clinical and medical reports

A prospective study to assess the impact of formoterol and budesonide nebulization as add on therapy in the management of acute exacerbation of COPD in a tertiary care hospital