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i Dedication  iv Acknowledgements  v List of Tables  vii List of Figures  ix Chapter 1 Genome stability in an unstable environment  1 Chapter 2 Tolerance and repair of DNA damage 10 Chapter 3 Gene expression patterns and developmental buffering 68 Chapter 4 Mitochondrial DNA sequence and stability  113 Chapter 5 Characterization of the Austrofundulus limnaeus genome  167 Chapter 6 Summary and future directions  193 References  202

Developmental Mechanisms that Support Genome Stability and Embryonic Survival in Stress-tolerant Embryos of the Annual Killifish &lt;i&gt;Austrofundulus limnaeus&lt;/i&gt;