English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A granular cell tumor of the breast parenchyma is a rare tumor accounting for 5-6% of all granular cell carcinoma and are mostly benign in nature. The malignant granular cell tumour is rare tumor that comprise 1-2% of all granular cell tumors. This is a case of a 35-year woman who presented with a palpable mass in the right breast. On wide local excision, a diagnosis of benign granular cell carcinoma was made. On follow up, with a disease free interval of one year, she developed local recurrence and she underwent simple mastectomy with adjuvant radiation therapy. Histopathological examination, confirmed benign granular carcinoma. This is one such case where histologically confirmed to be benign, but the clinical behaviour of the tumour favoured malignant variety. Hence adjuvant therapy should be considered for this benign appearing, malignant tumour. Granular cell tumour [GCT] or Granular Cell Schwannoma of the breast is a rare benign tumour of the neural cells. It is commonly noticed in the oral cavity and other soft tissues [1]. About 5-8% of GCTs occurs in breast [2]. Most of the GCT in the breast are benign in nature and occurrence of malignant GCT is even rarer. We encountered a GCT in the breast of a pre-menopausal women which morphologically did not show any conventional features of malignancy but it acted in an aggressive fashion. The aim of this case report was to increase awareness of the existence of a rare benign looking variant of GCT with clinical aggression.

Recurrent Benign Granular Cell Tumor of Breast with Malignancy – Does it Exist?