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This clinical case report describes and demonstrates successful use of recombinant human platelet-derived growth factor (rhPDGF-BB) in conjunction with autogenous bone, anorganic bone mineral, and barrier membranes to reconstruct severe alveolar bone defects. A combined sinus augmentation and vertical alveolar ridge augmentation was successfully performed. In addition, a significant amount of periodontal bone gain was achieved in close apposition to a previously denuded root surface, which is significant from a periodontal standpoint, given the possibility of vertical periodontal regeneration.

the journal of oral implantology/the journal of oral implantology

Simultaneous Vertical Guided Bone Regeneration and Guided Tissue Regeneration in the Posterior Maxilla Using Recombinant Human Platelet-Derived Growth Factor: A Case Report