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Chemical investigation on the ethyl acetate extract of the roots of Vietnamese Paederia scandens resulted in the isolation of one new anthraquinone, 1,3-Dihydroxy-2,4-dimethoxy-9,10-anthraquinone ( 1 ), together with three known anthraquinones, 2- H ydroxy-1,4-dimethoxy - 9,10- a nthra quin one ( 2 ), 1- M ethoxy-2-methoxymethyl-3-hydroxy -9,10- anthraquinone ( 3 ), 1-Hydroxy-2-hydroxymethyl-9,10-anthraquinone ( 4 ). Their structures were elucidated by the combination of 2D NMR, IR, UV and high resolution EI-MS spectroscopy. These anthraquinones ( 1 - 4 ) showed strong antimicrobial activity.

Anthraquinones from the roots of Paederia scandens