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The present paper describes chemical composition, NO inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide release, cytotoxic activity against MCF7 and Hep3B cell lines of the essential oil of Globba pendula Roxb. rhizomes. A total of 25 components of the essential oil were identified by using gas chromatography–mass spectrometry (GC-MS), accounting for 89.55 % of the total oil. -selinen (36.45 %) and ishwarane (10.76 %) were the main components. The essential oil was found to possess moderate NO inhibitory effect with IC50 of 41.68 ± 4.51 μg/ml, and significant cytotoxic activity against MCF7 and Hep3B cell lines with IC50 of 28.15 ± 1.08 and 35.24 ± 0.06 μg/ml, respectively. This is the first report on volatile compounds and biological activities of the essential oil of Globba pendula Roxb. rhizomes collected in An Giang province, Viet Nam.

VOLATILE COMPOUNDS AND BIOLOGICAL ACTIVITIES OF ESSENTIAL OIL OF GLOBBA PENDULA ROXB. COLLECTED AT AN GIANG PROVINCE