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Alphatocopherol is the main naturally occurring antioxidant substance capable of scavenging free radicals induced by pathological conditions; evidence is accumulating regarding the involvement of oxidative stress among the contraceptive users. The current research consisted of 75 contraceptive users and 42 apparently healthy age-matched controls. Serum levels of alphatocopherol are measured in accordance with method of Neil and Pearson (1907). Statistically (p<0.005) significant higher levels of alphatocopherol was observed among the contraceptive users compared to the control groups, No statistical difference was detected in different age groups. Alphatocopherol and other antioxidant supplementation should be encouraged among contraceptive users to alleviate oxidative stress.

Deficiency of Serum Alphatocopherol among Oral Hormonal Based Contraceptives Users in Sokoto Metropolis, Nigeria