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Apical membrane antigen (called AMA) found in Plasmodium falciparum malaria parasite, has been one of the leading malaria vaccine candidates and a subject of study for its potentials as an effective vaccine. The burden posed by malaria over the decades, moreso in the underdeveloped tropical world, re-emergence of malaria in regions it has been perceived to have once been eradicated, problem posed by resistance to effective drug by the parasite are among other reasons for spirited attempts by researchers to come up with good products from their efforts to support malaria control

Apical Membrane Antigen-1 of FalciparumMalaria Parasite (Pf83/Ama1): Efficacy as a Malaria Vaccine, Uncertainties and Attempts at Improving Efficacy