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Purpose: To perform a morphometric and chemical analysis of different bone graft materials used for guided bone regeneration treatments in dentistry. Methods: allogenic bone graft (OS, UNC and MO), xenogenic bone graft (BO) and alloplastic bone graft (GP), were analyzed. The bone tissue obtained from retained teeth surgery was used as a control. The morphometric analysis of particles was performed by using a stereoscopic magnifying glass and the average particle size was determined. Besides, X-ray dispersive energy microanalysis (EPXMA) was used in the chemical analysis. Bone graft particles were freeze dried, coated with carbon and analyzed in a scanning electron microscope in order to quantitatively determine (mmol/kg) the elements Ca and P. Ca/P ratio was determined for each experimental group. Results: Morphometric analysis showed that the mean bone particle size (mm) in increasing order was: UNC: 0.45; OS: 0.48; BO: 0.65; GP: 0.76; MO: 0.88. Microanalytical analysis showed that the Ca concentration in different experimental groups is less than the control. On the other hand, MO presented a statistically higher concentration of P than the other particles and the control. Ca/P ratio was statistically lower in MO compared to the other experimental groups. Conclusions: The morphological and chemical characterization of the bone particles allowed to know with greater precision the particle size, as well as the concentration of Ca and P present in them, data that should be used together with other clinical evaluations for guided bone regeneration treatments in dentistry. Ferrer, M. B.; Rodríguez, M. A.; Sorbera, L.; Martínez, R.; Rodríguez, I. A. Cátedra de Histología B, Facultad de Odontología, Universidad Nacional de Córdoba. Argentina Enviado: 13-03-2020 Revisado: 18-04-2020 Aceptado: 26-04-2020 Palabras clave: Partículas óseas de relleno; Microanálisis; Regeneración ósea guiada.

Morphometric and chemical characterization of bone grafting particles used in guided bone regeneration