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This study aimed to explore the correlation of blood quality with transforming growth factor (TGF-ß1) of platelet rich plasma (PRP) which was used for bone and periodontal tissue regeneration. Thirty nine subjects participated in this study. Data of age, gender, eritrocyt, leucocyt, hemoglobin, thrombocyt, and TGF-ß1 concentration were used to analyze the correlation using Spearman correlation test. This study found leucocyt, eritrocyt, hemoglobin, thrombocyt concentration mean was 8.19 g/dl, 5.31 g/dl, 14.48 g/dl, 326.32 g/dl, respectively. The TGF-ß1 concentration mean acquired from PRP was 31994.27 pg/ml. Based on Spearman correlation test, significant correlation was only observed in eritrocyt concentration variable with p value 0.023 (p<0.05) and it was higher in male than in female. It was concluded that TGF-ß1 concentration in PRP from normal subject was 31994.27 pg/ml. Based on leucocyt, eritrocyt, hemoglobin, and thrombocyt test to TGF-ß1, only eritrocyt showed the significant relationship. This finding also showed the linear correlation between the amoung of eritrocyt in blood with TGF-ß1 as the increased eritrocyt value was followed by the excalated TGF-ß1 value.

journal of dentomaxillofacial science

Hubungan kualitas darah dengan konsentrasi transforming growth factor-β pada platelet rich plasma yang digunakan untuk regenerasi tulang dan jaringan periodontal (Correlation of blood quality with concentration of transforming growth factor-ß1 in platelet rich plasma for bone and periodontal tissue regeneration)