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Cholesteatoma is a cyst which coated by stratified squamous epithelium containing keratin epithelial desquamation. The recurrence and bone destruction arerelevant features in cholesteatoma pathophysiology, which makes cholesteatoma tend to be dangerous and difficult to treat. Recent studies have shown that variations in cellular systems of matrix metalloproteinase-9 (MMP-9) production contribute to the pathophysiology of cholesteatoma, especially in of bone erosion. Objective: The aim of this study is to determine the correlation between MMP-9 with bone destruction in CSOM with cholesteatoma

bali medical journal

Correlation of Matrix Metalloproteinase-9 (MMP-9) expression and bone destruction in Chronic Suppurative Otitis Media (CSOM) patients with cholesteatoma at Adam Malik General Hospital Medan-Indonesia