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Background: Recently, etiology and pathogenesis of preeclampsia remain unknown. One of the theory indicating that hypoxia and ischemic placenta caused by abnormal cytotrophoblast invasion in preeclampsia. Soluble FMS-like tyrosine kinase-1 (sFlt-1) serum as a laboratory marker of hypoxia condition that contributes to the occurrence of endothelial damage and clinical manifestations in

High Level of Soluble FMS-Like Tyrosine Kinase-1 (sFlt-1) Serum in Pregnancy as a Risk Factor of Preeclampsia