English (United Kingdom)

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The English bulldog is notoriously predisposed to a number of disease conditions, including congenital defects, likely due to extreme genetic selection which has reduced genetic variability within this breed. The present report describes, for the first time, the main clinical and pathological features of congenital lung displacement in an English bulldog puppy. The defect involved the entire left lung, which was normally developed but rotated and shifted to the right hemithorax. The pathogenesis of congenital anomalies is largely unknown. characterisation of the genetic bases of these malformations is crucial for a reform of the breeding selection which is also aimed at correcting phenotypic abnormalities with a strong impact on individual health.

Congenital lung displacement in an English bulldog puppy