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Previous studies have suggested a possible association between chronic exposure to stress and increased blood pressure. The mechanisms are incompletely understood. There are two main stress responses in the human body: the acute stress response (sympathetic-adrenal medullary pathway) and the chronic stress response (hypothalamo-pituitary-adrenal pathway). The purpose of this study was to investigate the effect of chronic stress on blood pressure control as well as the benefits of adding anxiolytics to the standard antihypertensive therapy. The study includes 202 patients who visited a psychiatrist’s office regarding anxiety symptoms accompanied by high blood pressure occurring especially at night. The difference between the age for women (х= 66,34) and men (х = 60,14) is statistically significant (t (200) = -2.830, p = 0.006<0.05); 20.3% had close relatives with psychiatric disorders. 94.6 % of the patients had longstanding hypertension; 78.22 % were regularly taking antihypertensive drugs. The presence of anxiety was confirmed by Spielberger‘s State-Trait Anxiety Inventory (STAI). The patients were treated with four types of anxiolytic drugs with different modes of action, prescribed individually or in combination. The results indicate that regardless of the choice of anxiolytic agent, the blood pressure of over 90% of the patients was stabilized. The results suggest that anxiolytics, in addition to antihypertensive drugs, can produce clinically significant reductions in BP and improve emotional health in hypertensive patients with anxiety symptoms.

The role of anxiolytics in the treatment of patients with arterial hypertension accompanied by anxiety disorders