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The growing need of dietary supplements, self- medication and patients’ non-disclosure of herbal supplements use to doctors, the possible occurrence of adverse effects and the interaction with prescribed and over the counter drugs are among the reasons that require more rigorous assessment of the usefulness and safety of herbal supplements in order to best integrate them into common regimens. Lax control of production and distribution, and the lack of uniform legislation determine the need for changes in the regulation and harmonization of legislation in this area. Developing an appropriate postmarketing quality, efficacy and safety surveillance program will be a useful step, allowing the generation of important and relevant information for optimizing the risk - benefit ratio.

Herbal Supplements - Issues Related To Their Use