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The purpose of the present study was to establish the changes in some blood liver parameters in cows in different physiological conditions with subclinical (SCK) and clinical ketosis (CK). The study was performed on 157 Holstein cows with annual milk yield of 9,000–11,000 L. The animals were divided into 3 groups: I group – pregnant cows (from day 15 to day 0 pre-calving); II group – recently calved (from day 0 to day 15 postpartum) and III group – lactating (from day 30 to 45 postpartum). Blood concentrations of β-hydroxybutyric acid (ВНВА) (mmol/L), glucose (mmol/L), total protein (g/L), albumin (g/L) and total bilirubin (μmol/L) were assayed in all cows. The animals were divided in groups with SCK and CK according to their blood BHBA levels. It was established, that the concentrations of total bilirubin were statistically significantly elevated vs control groups, while blood glucose, total protein and albumin values decreased, reflecting the impaired liver function in cows with SCK and CK.

Evaluation of some blood liver parameters in cows with subclinical and clinical ketosis