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Background: Women who go through unsuccessful IVF treatment were at increased risk of depressive disorders. Objective: investigate the association between the unsuccessful IVF and depression among women with primary infertility. Methods: a cross-sectional study included infertile women attending fertility center. Socio-demographic and clinical variables were compiled. Self-Reporting Questionnaire (SRQ-20) to identify mental illnesses; DSM-V criteria for depression and Hamilton-17 Scale for severity of depression, were used. Results: high prevalence of depression among infertile women 80%. Unsuccessful IVF were 46%. About 26 % of infertile women with unsuccessful IVF were depressed. Depression was significantly associated with education, monthly income, duration of marriage, smoking, medication, chronic illness, and religion. Conclusion: Depressive disorders are the most frequently observed disorder among infertile women exposed to unsuccessful IVF

Major Depressive Disorder Association with Unsuccessful In-Vitro Fertilization (IVF) of Primary Infertile Women