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After evaluating problems in conceptualisation of Quality of Life outcomes andestablishing an operational definition of HRQoL, we focus the attention on the different dimensions of Response Shift and the theoretical Models to explaining it. We payspecial attention to Schwartz and Sprangers Model.If Gamma change is present, the construct under assessment is not stable forthe patient; so it has no sense to compare scores because if an individual changesconceptualization of QoL over the course of time, then answers to the same items bythe same individual may not be as comparable over time as originally thought. So, itis crucial to capture Response Shift before Alpha change is evaluated.The analytical approaches to assess Response Shift are discussed, paying specialattention to the statistical aspects. We found several shortcomings of Ahmavaara’sMethod for comparing factorial structures and we have developed some alternativesto capture Beta and Gamma components of Response Shift.Keywords: Health Related Quality of Life (HRQoL), Response Shift, Beta change,Gamma change, Dual Statis method.

El método Statis como alternativa para detectar "response shift" en estudios de calidad de vida relacionada con la salud