Memory for Prediction Error Minimization: From Depersonalization to the Delusion of Non-Existence

Depersonalization is an essential step in the development of the Cotard delusion. Based on Philip Gerrans ’ account ( this collection ), which is an integration of the appraisal theory, the simulation theory, and the predictive coding framework, this commentary aims to argue that the role of memory systems is to update the knowledge of prior probability required for successful predictions. This view of memory systems under the predictive coding framework provides an explanation of how experience is related to the construction of mental autobiographies, how anomalous experience can lead to delusions, and thus how the Cotard delusion arises from depersonalization.