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Objective: To identify adverse drug events (ADE) in adults patients hospitalized in medical and surgical units of a university hospital, as well as to characterize these events. Materials and Methods: A retrospective study was performed in a university hospital. The sample consisted of patients admitted to the medical and surgical units between October 1st, 2010 and January 31st, 2011. In order to identify the  DE, a set of triggers was applied, which are conditions that may indicate that an ADE occurred and make the review of records more objective and direct. These triggers can be an altered laboratory test, the use of an antidote or a clinical condition. Results: The study group consisted of two hundred and sixty-three patients, of whom fifty-eight (22.1%) had at least one ADE during hospitalization and 83 ADE were identified, resulting in a rate of 31.5 ADE per 100 patients. The most common events were nausea and vomiting, rash and itching and hypokalemia. As for the alleged drug, tramadol was most often related to the events. The events were more present in patients with urgent/emergency hospitalization, that had one or more comorbidities. Also, patients with ADE had a longer average time of hospitalization. Conclusion: The use of triggers to identify ADE presents as a useful strategy, from which it was possible to identify that 22.1% of patients had an ADE during hospitalization. This strategy to identify the events is likely to be implemented by patient safety core hospitals.

Uso de rastreadores para detecção de eventos adversos aos medicamentos em hospital universitário