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By means of a theoretical analysis, the function of trivalent vanadium oxyhydroxyde composite with the polymer of the acridine orange dye for electrochemical evaluation of entacapone antiparkinsonic drug has been evaluated. The electroanalytical process is based on the electrochemical reduction of the mentioned drug. From development and analysis of the correspondent mathematical model by means of linear stability theory and bifurcation analysis, it was possible to conclude that the composite is an efficient electrode modifier for entacapone determination. The oscillatory and monotonic instabilities in this system are also capable to realize.

revista colombiana de ciencias químico-farmacéuticas/revista colombiana de ciencias quimico-farmaceuticas

A descrição matemática do desempenho eletroanalítico do compósito poli(alaranjado da acridina)-oxihidróxido de vanádio na detecção eletrorredutiva da entacapona