English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The affinity of hemoglobin (Hb) for oxygen (O 2 ) is an important factor influencing the transport of this gas especially in hypoxia and in different diseases such as anemia or cystic fibrosis. By the affinity measurement, the determination of the Hb: O 2 dissociation curve is used. The presented method to establish the Hb: O 2 oxygen dissociation curve (CDO) simplifies the protocols normally used, since it eliminates the requirement of specific equipment to equilibrate blood with oxygen at fixed levels of oxygen pressure (PO 2 ). By using mathematical equations, it is possible to establish the saturation change of hemoglobin (SO 2 ) at increasing oxygen partial pressure. Similarly, the method determines typical aspects of the Hb: O 2 binding as the pH dependence (Bohr coefficient) and the association type of protein with its ligand by the Hill diagram. By this simplification, the method is applicable in laboratory practices in human and animal population, as well as in the investigation of different experimental conditions.

Método simplificado para determinar la Curva de Disociación de Oxígeno (CDO)