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We quantified and compared the hepatic melanomacrophage (MM) and glutathione S-transferase (GST) enzyme activity (two oxidative stress biomarkers) in the liver of Leptodatylus chaquensis adults (Anura, Leptodactylidae) collected in a rice field (CA) in San Javier department, Santa Fe (Argentina), seven days after the application of chlorpyrifos and in a reference site (SR). The histological analysis revealed a significant amount ( p = 0.028) and area occupied by MM ( p = 0.017) in livers of CA compared to SR. Furthermore, a significant inhibition of GST activity was recorded in the CA frogs compared to the SR ( p = 0.030). The histopathological and enzymatic effects provide evidences of ecotoxicological risk for anurans in rice field with CPF application.

acta biológica colombiana/acta biológica colombiana

Melanomacrófagos hepáticos y actividad de la enzima Glutation S-Transferasa en Leptodactylus chaquensis (Anura, Leptodactylidae) como biomarcadores de estrés oxidativo por la exposición a clorpirifos