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The work is aimed at investigation of diagnostic efficiency of a new azimuthally stable Mueller-matrix method for analysis of laser autofluorescence coordinate distributions corresponding to biological tissue histological sections. A new model of generalized optical anisotropy observed in biological tissue protein networks has been proposed to study the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism has been taken into account. The interrelations between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy have been ascertained. The statistic analysis of coordinate distributions inherent to these Mueller-matrix rotation invariants has been proposed. Thereupon the quantitative criteria (statistic moments of the 1 st to 4 th orders) of differentiation of histological sections of uterus wall tumor – group 1 (dysplasia) and group 2 (adenocarcinoma) have been found.

Differentiation of Mueller-matrix invariants of biological tissues fibrillar networks with different phase and amplitude anisotropy