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Надійшла 26.01.2018 Прийнята до друку 19.02.2018 Received January, 26, 2018 Accepted February, 19, 2018 Osteoarthrosis is clinically characterized by a feeling of pain during walking, stiffness and limited movements in the affected joint, that inevitably leads to a decrease in the quality of life and disability, and future endoprosthetic replacement. The search for effective methods of conservative treatment has remained an urgent task of current orthopedics. In attempts to avoid a surgical treatment for patients with joint osteoarthritis, the conservative methods such as weight control, exercise therapy, physiotherapy, fixation, orthotics, administration of non-steroidal anti-inflammatory drugs and intraarticular injections of either corticosteroids or hyaluronic acid (HA) are suggested [1]. In general, the aim of each of these therapeutic methods is to temporarily reduce the pain and improve the function of the affected joint. The therapeutic effect of hyaluronic acid remains uncertain. This type of treatment is called as ‘viscosupplementation’, i. e. increasing the viscosity of a synovial fluid. Consequently, hyaluronic acid, regardless of the manufacturer, concentration and auxiliary components, just lengthens the ‘life time’ of the joint for a certain period, delaying the need for endoprosthetics, but does not contribute to its recovery [3]. Therefore, it is relevant to search for other possibility of treating degenerative pathologies. One of the solutions to this problem may be applying the tools of regenerative medicine, which is considered as an alternative to traditional treatment [2]. Prolotherapy is the novel trend in regenerative medicine, УДК 616.72-002-003.93-08:547.995.15 С.М. Марциняк, С.П. Чорнобай, Є.Л. Голюк, Г.Г. Бондарєв* Сучасний підхід до консервативного лікування дегенеративних захворювань суглобів із застосуванням технологій регенеративної медицини

Modern Approach to Conservative Treatment of Degenerative Diseases of Joints Using Regenerative Medicine Techniques