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Lowe Syndrome (LS) is a rare genetic disorder involving ocular, renal and central nervous system manifestations. Dental findings have also been described while orofacial skeletal characteristics have not yet attracted considerable attention and estimation. This paper presents the dental findings and the maxillofacial skeletal characteristics evaluated on panoramic and lateral cephalometric radiographies of male twins in mixed dentition. It also provides results of the orthodontic treatment performed to ameliorate the dental and skeletal relationships. Dental and skeletal manifestations of the present male twins suffering from LS as well as the orthodontic treatment approach may enrich the pool of the existing data on this rare syndrome. Moreover, enhanced knowledge may help dentists and health professionals who participate in the overall treatment for these patients to carry out improved treatment plans and provide the best possible quality of life for these patients.

Dental and Orofacial Skeletal Findings in Young Male Twins with Mild Lowe Syndrome