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Eighteen congeners Polychlorinated biphenyls (PCBs) congeners were analyzed in 38 human milk samples collected from different ages living in Eastern and Central provinces in Saudi Arabia. The PCB profile was dominated by higher chlorinated congeners. Non-ortho PCB congeners which have the highest Toxic Equivalency Factor (TEF) values were detected in all of individual samples. PCB-81 and PCB-153, the most dominating PCB congeners, which might therefore be used as an indicator for sum PCBs. Toxic Equivalents Factor (TEF) for mono-ortho substituted PCB congeners indicated higher exposure to toxic PCBs in Eastern province rather the Central due to main petroleum industry activities, but estimated daily intakes for both provinces indicate that infants consuFming mother’s milk are not at risk of adverse effects caused by PCBs. Our study builds the first database in Saudi Arabia research of human milk samples.

Congener Specific Determination of Polychlorinated Biphenyls (PCBs) in Human Milk