Open AccessPPIs Prevent Aspirin-Induced Gastrointestinal Bleeding Better than H2RAs. A Systematic Review and Meta-analysis
Author(s) -
Imre Szabó,
Róbert Mátics,
Péter Hegyi,
András Garami,
Anita Illés,
Patrícia Sarlós,
Judit Bajor,
Ákos Szűcs,
Dóra Mosztbacher,
Katalin Márta,
Kata Szemes,
Kata Csekő,
Bálint Kővári,
Zoltán Rumbus,
Áron Vincze
Publication year - 2017
Publication title -
journal of gastrointestinal and liver diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 48
eISSN - 1842-1121
pISSN - 1841-8724
DOI - 10.15403/jgld.2014.1121.264.hra
Subject(s) - medicine , aspirin , meta analysis , gastroenterology , odds ratio , gastrointestinal bleeding , randomized controlled trial , observational study
Aspirin is one of the most widely used medication for its analgesic and anti-platelet properties and thus a major cause for gastrointestinal (GI) bleeding. This study compared the preventive effect of histamine-2 receptor antagonists (H2RAs) and proton-pump inhibitors (PPIs) against chronic low-dose aspirin (LDA)-related GI bleeding and ulcer formation.
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