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The incidence of spontaneously occurring ventricular septal defects (VSD) in PIKA neonates and its fate during development are investigated. A total of 160 PIKAs were used in the present study. They consisted of three groups; first, 56 live neonates, second, 37 3-week-old live animals and third, 68 animals which had died during the first two weeks after birth from unknown causes. As high as 8.9% (5 cases out of 56) of the live neonates revealed isolated ventricular septal defects of membranous type. Decreased incidence (2.7%) was seen in 3-week-old PIKAs. Its implication and significance are evaluated in the discussion.

Spontaneous Closure of Isolated Ventricular Septal Defect in the Pika (<I>Ochotona rufescens rufescens</I>)