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Reproductivities of mother mice of inbred strains were investigated and a project for their efficient production was made on the basis of the data of reproductivity. Inbred strains of mice used were C3HeB/FeJax, C3H/HeMs, C57BL/6Jax, CBA, BALB/cHe, A, Rill and DBA/2, which were maintained by sister x brother mating in our laboratory . After 70 days of age, each female was mated with a male and concurrent pregnancy was planned until the 3rd lactation. Interval between litters was approximately 4 weeks in all strains except BALB/cHe , of which interval was about 5 weeks (Fig. 1). There was marked difference in litter size among strains; the largest was 6.4 in C3HeB/FeJax and C3H/HeMs and the smallest was 4 .2 in DBA/2 (Fig. 2). Normal parturition ratio was better in C3HeB/FeJax, C3H/HeMs, CBA, C57BL/6Jax and A than in BALB/cHe, RIII and DBA/2 (Fig. 3). The rearing ratio on day 20 of lactation was lower in RIII, DBA/2 and A than in the other strains (Fig . 4). As shown in Table 2, strains with larger mothers had a trend to produce larger pups than strains with smaller mothers, while there was no large differences among strains in the pups' growth ratio. From the data shown in Tables 1 and 2 and Figs. 1-4, it would be considered that the reproductivity was better in order of C3HeB/FeJax, C3H/HeMs  DBA/2. The results of interval between litters indicate that numbers of groups starting mating are 5 and 4 in BALB/cHe and in the other strains, respectively, to produce weanling pups every week (Fig . 5). Number of parents required per group is obtained by the following formula;

Reproductivity in Inbred Strains of Mice and Project for Their Efficient Production