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LC 50 values for the adult millipede Anoplodesmus tanjoricus were calculated (0.025 ppm concentration up to 96 hours) after exposure to an organochlorine insecticides endosulphan. The neurosecretory activites of A types of cells. They are differentiation A1,A2,A3,A4 was observed to be increased at the corresponding concentration for exposure period 24,48 and 96 hours the cell sizes are increased and 72 hours the cell sizes are decreased. The cytological picture was altered by formation of vacuoles, undulation and distortion of the cell wall in the A cells types. The neurosecretory activity in B cell showed the synthetic activity by 24, 48,72 and 96 hours ,it decreased cell size the cytoarchitecture was disturbed which include clumping of chromatin material, undulation of cell envelop and damage of neurophile. The neurosecretory activity in c cells (C1and C2) showed increased synthetic activity in the 24,48, and 96 hours and in 72 hours decreased synthetic activity, this may be an initial response in the emergency to pesticidial toxicity.

Effect of endosulphan on the neurosecretory cells profile of the millipede Anoplodesmus tanjoricus (Diplopoda: Myriapodes)