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Serum high density lipoprotein cholesterol (HDL.CHO) of health individuals (342 males and 483 females) was measured with other serum lipid contents as well as several factors which may be possibly associated with atherosclerotic disorders including ischemic heart disease. As a cholesterol risk factor index (CRFI), (total cholesterol-HDL.CHO)/total cholesterol was studied. With the increase of CRFI in male plus female group, highly significant correlations were detected in the following factors: i.e. cholesterol, triglyceride, uric acid in serum; the number of erythrocytes and the components; obesity and blood pressure. HDL-CHO was negatively related to the increase of CRFI. In female, all these correlations to CRFI were found. In male, however, only 3 categories such as serum lipid components, the number of erythrocytes and obesity were related to CRFI. With the advance of age, significant changes were found mainly in female: in CRFI, cholesterol, triglyceride, uric acid, glucoxyloxal transferase, erythrocyte components, and blood pressure. In male, only the last two factors were correlated with aging. Thus, the relation of CRFI to other categories depended not only sex but also aging.

Serum high density lipoprotein cholesterol. As a cholesterol risk factor index for atherosclerotic diseases.