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The effect of oral administration of diltiazem, a new 1,5-benzothiazepine derivative, on the frequency of anginal attack at rest was studied in 8 patients. Our own experience showed that diltiazem gave excellent results in patients with ST elevation (variant type) but its effect was insufficient in the patients whose ST segment was depressed during the attack.

Beneficial Effect of Diltiazem, a New Antianginal Drug, on Angina Pectoris at Rest